Basic Science

Casarett & Doull's Essentials of Toxicology,
Second Edition

John B. Watkins III,
Curtis Klaassen
ISBN: 0071622403 / 9780071622400
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Casarett & Doull's Essentials of Toxicology,
Second Edition

Table of Contents

UNIT I
GENERAL PRINCIPLES OF TOXICOLOGY

1. History and Scope of Toxicology
Michael A. Gallo

2. Principles of Toxicology
David L. Eaton and Steven G. Gilbert

3. Mechanisms of Toxicity
Zoltán Gregus

4. Risk Assessment
Elaine M. Faustman and Gilbert S. Omenn


UNIT 2
DISPOSITION OF TOXICANTS

5. Absorption, Distribution, and Excretion of Toxicants
Lois D. Lehman-McKeeman

6. Biotransformation of Xenobiotics
Andrew Parkinson and Brian W. Ogilvie

7. Toxicokinetics
Danny D. Shen


UNIT 3
NONORGAN-DIRECTED TOXICITY

8. Chemical Carcinogenesis
James E. Klaunig and Lisa M. Kamendulis

9. Genetic Toxicology
R. Julian Preston and George R. Hoff mann

10. Developmental Toxicology
John M. Rogers and Robert J. Kavlock


UNIT 4
TARGET ORGAN TOXICITY

11. Toxic Responses of the Blood
John C. Bloom and John T. Brandt

12. Toxic Responses of the Immune System
Norbert E. Kaminski, Barbara L. Faubert Kaplan, and Michael P. Holsapple

13. Toxic Responses of the Liver
Hartmut Jaeschke

14. Toxic Responses of the Kidney
Rick G. Schnellmann

15. Toxic Responses of the Respiratory System
Hanspeter R. Witschi, Kent E. Pinkerton, Laura S. Van Winkle, and Jerold A. Last

16. Toxic Responses of the Nervous System
Virginia C. Moser, Michael Aschner, Rudy J. Richardson, and Martin A. Philbert

17. Toxic Responses of the Ocular and Visual System
Donald A. Fox and William K. Boyes

18. Toxic Responses of the Heart and Vascular System
Y. James Kang

19. Toxic Responses of the Skin
Robert H. Rice and Th eodora M. Mauro

20. Toxic Responses of the Reproductive System
Paul M. D. Foster and L. Earl Gray Jr.

21. Toxic Responses of the Endocrine System
Charles C. Capen


UNIT 5
TOXIC AGENTS

22. Toxic Effects of Pesticides
Lucio G. Costa

23. Toxic Effects of Metals
Jie Liu, Robert A. Goyer, and Michael P. Waalkes

24. Toxic Effects of Solvents and Vapors
James V. Bruckner, S. Satheesh Anand and D. Alan Warren

25. Toxic Effects of Radiation and Radioactive Materials
Naomi H. Harley

26. Toxic Effects of Terrestrial Animal Venoms and Poisons
John B. Watkins III

27. Toxic Effects of Plants, Fungi, and Algae
Stata Norton


UNIT 6
ENVIRONMENTAL TOXICOLOGY

28. Air Pollution
Daniel L. Costa

29. Ecotoxicology
Richard T. Di Giulio and Michael C. Newman


UNIT 7
APPLICATIONS OF TOXICOLOGY

30. Food Toxicology
Frank N. Kotsonis and George A. Burdock

31. Analytic/Forensic Toxicology
Alphonse Poklis

32. Clinical Toxicology
Louis R. Cantilena Jr.

33. Occupational Toxicology
Peter S. Th orne

Answers to Chapter Questions

Index 439