Harper's Illustrated Biochemistry, 28th Edition

Robert K. Murray Victor W. Rodwell David Bender Kathleen M. Botham P. Anthony Weil Peter J. Kennelly ISBN: 0-07-162591-7 Purchase

New Key Features in This Edition!

• Influence of the Human Genome Project on various biomedical fields
• Revision of the use of enzymes in medical diagnosis
• New material on computer-aided drug discovery
• Compilation of some conformational diseases
• New material on advanced glycation end-products and their importance in diabetes mellitus
• New material on the attachment of influenza virus to human cells
• Some major challenges facing medicine

Important biochemical updates include:

• Expanded coverage of mass spectrometry, a key analytical method in contemporary biochemistry
• New figures revealing various aspects of protein structure
• Expanded coverage of active sites of enzymes and transition states
• New information on methods of assaying enzymes
• Expanded coverage of aspects of enzyme kinetics
• New information on micro- and silencing RNAs
• New information on eukaryotic transcription mechanisms, including the biogenesis of mRNA and the role of nucleosomes
• Description of activities of miRNAs
• New material on next generation sequencing (NGS) platforms
• New material on chromatin immunoprecipitation (CHIP) technology and its uses
• New information on subcellular localization of key signaling enzymes (kinases, phosphatases)
• New information on how hormones affect gene transcription